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当前位置:首页 > 产品中心(Products) > 细胞定制Cell Customization(Cell Customization) > 稳转细胞株(Transfected Stable Cell Lines) > 示踪/报告细胞株(Report Transfection cell line) > PAI-1报告细胞系(Luc)-Mv1 Lu
产品描述/Products Description
PAI-1 Reporter (Luc)-Mv1 Lu cell line is designed for monitoring transforming growth factor β (TGF-β)-induced plasminogen activator inhibitor-1 (PAI-1) expression. Transforming growth factor-β (TGF-β) is a potent regulator of cellular differentiation, proliferation, migration, and protein expression.
PAI-1 Reporter (Luc) –Mv1 Lu cell line contains a firefly luciferase gene under the control of PAI-1 responsive elements stably integrated into Mv1 Lu (NBL-7) cells, showing TGF-β pathway response. This cell line is validated for the TGF-β response to the induction of PAI-1 gene expression through luciferase activity.