CATH.a小鼠神经细胞

该细胞系是由转基因小鼠大脑中产生的肿瘤培养物建立起来的细胞株，该转基因包含与783bp部分酪氨酸羟化酶基因相关的SV40T抗原编码序列,细胞表达酪氨酸羟化酶和多巴胺β羟化酶，并含有神经丝。

动物种别/Organism 小鼠

组织来源 Tissue and Cell Type 神经细胞

形态/Morphology 上皮细胞样；贴壁生长

培养基和添加剂/Complete Growth Medium and Culture Conditions：

87%RPMI1640(MD0200)+8%马血清（SD0300）+4%FBS(SD0200)+2 mM/L-谷氨酰胺（SD0007)+1%G/A（SD0038）

完全培养基：RPMI1640完全培养基（MD0213)

冻存条件：基础培养基+5%DMSO+20%FBS(SD0200)

完全冻存液：免程序降温细胞冻存液（低血清）(SD0001)

注意事项：此产品仅供科研使用

PubMed=7680068; DOI=10.1523/JNEUROSCI.13-03-01280.1993

Suri C., Fung B.P., Tischler A.S., Chikaraishi D.M.

Catecholaminergic cell lines from the brain and adrenal glands of tyrosine hydroxylase-SV40 T antigen transgenic mice.

J. Neurosci. 13:1280-1291(1993)

Patent=US5591626

Chikaraishi D.M.

Expression of a target gene in transgenic mammals with 5' flanking sequences of the rat tyrosine hydroxylase gene.

Patent number US5591626, 07-Jan-1997

PubMed=9006967; DOI=10.1523/JNEUROSCI.17-04-01217.1997

Qi Y., Wang J.K.T., McMillian M., Chikaraishi D.M.

Characterization of a CNS cell line, CAD, in which morphological differentiation is initiated by serum deprivation.

J. Neurosci. 17:1217-1225(1997)