小鼠成骨细胞到骨细胞样细胞系MLO-A5

背景介绍/context：

MLO-A5 cell line is a model for the osteoblast to osteocyte differentiation process, the mineralization process, and the effects of mechanical loading on biomineralization.Derived from a transgenic mouse in which the immortalizing T-antigen was expressed under control of the osteocalcin promoter.Osteocytes are the most abundant bone cells in the body but also the most challenging to study because they are embedded in a mineralized matrix making them to difficult to isolate. This cell line MLO-A5 make it easier to study osteocyte function.

MLO-A5细胞系是成骨细胞向骨细胞分化过程、矿化过程以及机械载荷对生物矿化影响的模型。在骨钙素启动子的控制下表达永生化的t抗原的转基因小鼠。骨细胞是体内最丰富的骨细胞，但也是最具挑战性的研究，因为它们嵌入矿化基质中，难以分离。MLO-A5细胞系使骨细胞功能的研究更加容易。

动物种别/Organism  小鼠

组织来源 Tissue and Cell Type 骨

形态/Morphology 贴壁生长 

注意事项：此产品仅供科研使用