MH-S细胞株

背景介绍/context：

The MH-S cell line was obtained from a 7 week-old male BALB/c J mouse by bronchoalveolar lavage followed by SV-40 transformation of an adherent cell enriched population of alveolar macrophages. Many properties of alveolar macrophages are expressed with the cells being phagocytic, esterase positive and peroxidase negative. The intracellular T-antigen and cell surface Ia and Mac-1 antigens are expressed as well as Fc receptors. IL-1 is constitutively expressed and can be increased by stimulation with lipopolysaccharides (LPS). A cellulose dependant suppression of the in vitro plaque-forming cell (PFC) i-espouse by MH-S cells has also been reported.

从7周龄BALB/c J雄性小鼠中获得MH-S细胞株，经支气管肺泡灌洗后，再由富含肺泡巨噬细胞的黏附细胞SV-40转化。肺泡巨噬细胞的许多特性表现为吞噬、酯酶阳性和过氧化物酶阴性。细胞内t抗原、细胞表面Ia和mc -1抗原以及Fc受体均有表达。IL-1组成性表达，并可通过脂多糖(LPS)刺激而增加。在体外血小板形成细胞(PFC)中，纤维素依赖抑制的MH-S细胞也有报道。

动物种别/Organism  BALB/c J雄性小鼠

组织来源 Tissue and Cell Type 肺泡巨噬细胞

形态/Morphology 贴壁生长 

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