人羊膜间充质基质细胞

背景介绍/context：

Multipotent mesenchymal stromal cells, also known as mesenchymal stem cells (MSC), are a well-characterized population of adult stem cells. They have the potential to develop into mature cells that produce fat, cartilage, bone, tendons, and muscle. These properties, in combination with their developmental plasticity, have generated tremendous interest because of the potential use of MSC in regenerative medicine to replace damaged tissues. MSCs can differentiate into chondrocytes or osteoblasts. MSC have the capability for renewal and differentiation into various lineages of mesenchymal tissues. MSC derived from the amnion and chorion express CD271, possess characteristics of cardiomyocytes, and have various antiangiogenic and anti-inflammatory proteins. 

HAMSC from AcceGen are isolated from human amniotic membrane. HAMSC are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume. HAMSC are characterized by immunofluorescence with antibodies specific to CD73, CD90, CD105 and lipid staining after differentiation. HAMSC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HAMSC are guaranteed to further expand for 15 population doublings under the conditions provided by AcceGen.

多能间充质基质细胞，又称间充质干细胞(MSC)，是一种具有良好特征的成体干细胞。它们有潜力发展成成熟细胞，产生脂肪、软骨、骨骼、肌腱和肌肉。由于MSC在再生医学中用于替代受损组织的潜力，这些特性连同其发育可塑性引起了人们极大的兴趣。间充质干细胞可分化为软骨细胞或成骨细胞。间充质干细胞具有更新和分化为不同系间充质组织的能力。

来自羊膜和绒毛膜的间充质干细胞表达CD271，具有心肌细胞特征，并含有多种抗血管生成和抗炎蛋白。从人羊膜中分离得到AcceGen中的HAMSC。HAMSC被冷冻保存在第1通道并冷冻交付。每瓶含有5x10 ^5个细胞，每毫升体积。HAMSC具有CD73、CD90、CD105特异性抗体的免疫荧光和分化后脂质染色的特征。HAMSC对HIV-1、HBV、HCV、支原体、细菌、酵母和真菌均呈阴性。在AcceGen提供的条件下，HAMSC保证进一步扩大到15倍人口。

动物种别/Organism  人

组织来源 Tissue and Cell Type 羊膜和绒毛膜

形态/Morphology 贴壁生长 

注意事项：此产品仅供科研使用